Members of your household who are aged 5 years or over are also able to have the COVID-19 vaccine. VAT no: 668265007. Macmillan Cancer Support 2020 Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Call freephone 9 to 5 Monday to Friday or email us. Isle of Man company number 4694F. Public Health England We know that it is common to struggle with your mental health when you have cancer or care for someone with cancer. Your doctor or nurse will talk to you about this. I agree with the people who are saying not to stay in bed. oxaliplatin and capecitabine (CAPOX) before CRT and TME in pa-tients with poor prognosis rectal cancer in a single-arm phase II trial (EXPERT).30 Patients received four cycles of CAPOX followed by capecitabine CRT, TME, and 12 weeks of adjuvant capecitabine. Also operating in Northern Ireland. I hope it's the same for you! Your doctor, nurse or pharmacist can tell you more about this. This treatment may affect your skin and nails. Accessed April 2021, Immunisation against infectious disease: Chapter 6: General contraindications to vaccination Capecitabine is FDA-approved as first-line treatment of patients with metastatic colorectal carcinoma when treatment with 5-FU therapy alone is preferred. irinotecan single agent 2 weekly or 3 weekly protocol. The only thing I can think of is to get a pair of gloves that you can use easily that will insulate against the cold. They will slow or stop your drip for a while andgive you medicine to help relieve your symptoms. I am a sports junkie and love baseball. Chewing gum can help to keep the mouth moist. Toxic effects of capecitabine and fluorouracil were similar. XELOX is usually given every 21 days. sharp chest pain, which may be worse when you cough or take a deep breath. If I'm tired I take a nap, but I try to be as active as I can. I liked Gold Bond Aloe, but everyone has their favorite. If cisplatin is substituted by oxaliplatin and 5-FU by . Your doctor will prescribe eye drops to help prevent this. Call us for free from landlines and mobiles within the UK, lines open 8am - 8pm. Cancer and some cancer treatments can increase the risk of a blood clot. Maybe you'll be one who doesn't react badly. You may get a bitter or metal taste in your mouth. If the number of red blood cells is low, this is called anaemia. I once got a huge blister at the gym and couldn't use the treadmill for a couple of weeks. It is important to get any infection treated as soon as possible. They may give you a copy of the treatment plan to take home with you. Your doctor can give you drugs to help control some side effects. These are both inactivated vaccinations that can help reduce the risk of infection. The nurse or pharmacist gives you the capecitabine tablets to take at home. I have clothes ready for the cold. They also depend on what othertreatment you are having. If your blood results are okay, the pharmacist will prepare your chemotherapy. tell your nurse or doctor they can give you a mouthwash or medicines to help. If your white blood cell count is low, your doctor may delay your treatment for a short time, until your cell count increases. What's going on near you? Signs of a severe skin reaction include peeling or blistering of the skin. Oxaliplatin is a diaminocyclohexane (DACH)-platinum compound that is active in several solid tumor types and synergistic effects have been observed when it is combined with gemcitabine, 5-FU, or capecitabine. These may be done before, during and after treatment. They can give you advice and may give you creams or medicines to help. If you are very anaemic, you may need a drip to give you extra red blood cells. All patients received standard gastrectomy with D2 lymphadenectomy. The National Comprehensive Cancer Network (NCCN) has released new guidelines for ampullary adenocarcinoma, a disease accounting for just 0.2% of all gastrointestinal malignancies. Your doctor, pharmacist or nurse will go through the possible side effects. However, there has only been experience in Japanese patients with using CapOX therapy, in which capecitabine and oxaliplatin are used in . This treatment may also cause blurry vision. Make sure to hang out and ask questions during all of this, you got this man. You should take them within 30 minutes of finishing a meal. avoid alcohol, tobacco, and foods that irritate your mouth and throat. A company limited by guarantee, registered in England and Wales company number 2400969. Ask them if you can take paracetamol to help loweryour temperature. Isle of Man company number 4694F. You can talk to your cancer doctor about your risk of having DPD deficiency before you start treatment. Only if you think the stress is going to affect you now. We cannot list every side effect for this treatment. Each cycle lasts 3 weeks (21 days). But it is important that you know about it. Your doctor will tell you the amount (dose) of capecitabine you need to take. Progression-free survival and response rates did not differ significantly among the regimens. This issue has come up here in the past and hopefully others can chime in. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. FOLFOX Protocol V1.2. The warm weather helps for sure. I'm one who had relatively mild effects from the Folfox/pump regime, limited to some nueropathy in hands and feet, cold sensitivity in my hands and throat, and fatigue, especially when it was real warm[SoCal area]. It is often worse towards the end of treatment and for some weeks after it has finished. Arms A and B respectively received 8 cycles of adjuvant XELOX (capecitabine 1000 mg/m 2, bid, d1-14, oxaliplatin 130 mg/m 2, d1, q3W) or SOX (TS-1: 40-60 mg bid, d1-14, oxaliplatin: 130 mg/m 2 d1, q3W). First published: March 2013 and regularly updated on the Gov.UK website, Handbook of Cancer Chemotherapy (8th edition) Prospective data on prevalence of oxaliplatin induced acute and long-term neuropathy in a real-life patient population and its effects on quality of life (QOL) and survival is limited, and scarce in CAPOX versus . Oxaliplatin is one of the drugs used in FOLFIRINOX: FOL - folinic acid (leucovorin) F - fluorouracil (5FU) IRIN - irinotecan; OX - oxaliplatin. But these services are not available in every hospital, so you would need to ask your doctor about this. I had it in the winter and it was not fun. Before starting this treatment, you should have a blood test to check whether you have low levels of an enzyme called DPD. I was less tired and able to work more. Less commonly you might get pain from other areas of the body such as your joints, bones, limbs, or chest. Macmillan Cancer Support 2020 Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). I actually responded well to avastin. Great! They may give the next doses of oxaliplatin over 4 to 6 hours to reduce the chance of throat spasms. We conducted the first ever randomised trial specific for this rare subgroup (4 regimens). Traci. Tell your doctor or nurse about any changes to your hands or feet. They may suggest that you dissolve the capecitabine tablets in water. Very scary sight (to me). It is important to keep hands and feet well moisturised. You might have one or more of them. At the end of the rest period, you start your second cycle of XELOX. Oxaliplatin can cause pain at the place where the injection is given or along the vein. They can give you painkillers to help. Don't push yourself, rest when you start to feel tired and ask others for help. Oxaliplatin is normally given together with other drugs to treat pancreatic cancer. Your doctor will talk to you about this treatment and its possible side effects before you agree to have treatment. Tell your healthcare team if you're finding it difficult to walk or complete fiddly tasks such as doing up buttons. This is for 2 weeks following their vaccination. You may gain weight while having this treatment. And I am not going to be polite like Tru, STAY OUT OF BED!!! Your healthcare team will tell you what moisturiserto use. So far as is permitted by law, Macmillan does not accept liability in relation to the use of any information contained in this publication or third party information or websites included or referred to in it. It helps by slowing the growth of blood vessels to provide food for the tumors. Eat less fibre, avoid raw fruits, fruit juice, cereals and vegetables, and drink plentyto replace the fluid lost. Stay as active as you can for as long as you can. Some cancer drugs can affect whether you can get pregnantor make someone pregnant. Abstract. I guess in life I always try to hope for the best and prepare for the worst. The oxilaplatin was unpleasant with the neuropathy side effects but it's different for everyone and having to do it now that spring is here will help. This will protect your partner if any of the drug is in your semen or vaginal fluid. This combination might also be called CAPOX, CAPE-OX or OxCap. Electronic Medicines Compendium You may get pain or discomfort in your tummy (abdomen). You might have treatment through a long plastic tubethat goesinto a large vein in your chest. Although I mentioned it to the nurse who did my infusions I never mentioned it to the oncologist. Depending on your needs, you may have between 4 and 8 cycles. Also operating in Northern Ireland. April 2017 #1. You may have a skin rash which then blisters and your skin can peel. All had . We make every effort to ensure that the information we provide is accurate and up-to-date but it should not be relied upon as a substitute for specialist professional advice tailored to your situation. This could be a sign of infection or more rarely lung problems such as asthma, a blood clot in the lung, a collapsed lung (pneumothorax), or changes to the lung tissue, making it less flexible. This can be a: You mighthave treatmentthrough a thin short tube (a cannula) that goes into a vein in your arm. So you may start treatment with a lower amount (dose) of the drug or have a different treatment. Contact the hospital straight away on the 24-hour contact number you have been given if: It is important to follow any specific advice your cancer treatment team gives you. Your nurse or doctor will discuss your treatment plan with you. 2011 Jun;9(6):492-500. If you have breathing difficulties, take long, deep breaths through your nose. This can cause symptoms including: Tell your doctor or nurse straight away if you notice any of these symptoms. If this isn't possible, wash your hands well after changing their nappy. Roland KKeel . A low white blood cell count is sometimes called neutropenia. Quite a few members of our forum have taken Capecitabine, for example @Cutie mentions it on this thread . Signs of a reaction can include: Your nurse will check you for signs of a reaction during your treatment. You may get some of the side effects we mention, but you are unlikely to get all of them. A sudden feeling of cold with shivering often with a rise in temperature and sweating. Drink plenty of fluids and eat as much fresh fruit and vegetables as you can. I was also stage three when I was diagnose over three years ago. Lippincott, Williams and Wilkins, 2012. It is easier to prevent sickness than to treat it after it has started. Let your nurse know straight away if it's affecting your breathing and swallowing. To meet the growing demand for prescription and non-prescription weight loss products, pharmaceutical companies invest millions of $ in the development and research of new diet pills. avoid alcohol, caffeine, milk products, high-fat foods and high-fibre foods. You may find it hard to fasten buttons or do other fiddly tasks. Skinproblemsincludea skin rash which might be red and itchy. drinking plenty of fluids, especially water. The tube stays in place throughout the course of treatment. The second week I was eating normally. I had a touch of each possible side effect, but limited. your temperature goes over 37.5C (99.5F), you suddenly feel unwell, even with a normal temperature. An infection can be very serious when the number of white blood cells is low. Constipation is easier to sort out if you treat it early. Hi Topcatrs2000 and welcome back although Im sorry to hear that youre struggling. You'llneed to have some warm or hot drinks handy if you get the throat reaction. The oxaliplatin is a bit rough. Thats a very annoying side effect. I guess that makes me T3 N1b M0. Your nurse usually gives you anti-sickness (anti-emetic) drugs before the chemotherapy. vitamins, herbal drugs and complementary therapies. VAT no: 668265007, Coping with the news you have incurable cancer, Spring Picture Festival - Share your Spring. Its only temporary but can feel quite frightening. It is easier to prevent sickness rather than treating it once it has started. God bless us all troopers!! Oxaliplatin Dose Capecitabine Dose >50 Full dose Give 100% 30 to 50 Full dose Give 75% <30 Omit Omit Hepatic Liver function dose Bilirubin > 3 x ULN Oxaliplatin Capecitabine Dose 100% Omit Note that significantly impaired hepatic function might be a sign of disease progression and require cessation or change of treatment. They may give the drug more slowly or flush it through with more fluid to reduce pain. That's a very annoying side effect. Unfortunately I now have more lung tumours so waiting for an appointment to see what is recommended. You may have: Tell your doctor if you have any unexplained bruising or bleeding. They may give you painkillers to help. You should contact youradvice line urgently if you think you have an infection. Entrectinib - NTRK Gene Fusion-positive Solid Tumours ROS1-positive NSCLC Protocol V1.1. You may need a drip to give you extra platelets. Many facilities will have programs with finanical assistance, like MSK can set up payment plans and the rest to make it easier. They sometimes need to lower the dose of the drug. There were some days when I was tired and took a nap. It is a treatment for bowel cancer (colorectal cancer). Its a horrible condition . They can prescribe a laxative. I wish you luck as you start your chemo jouney. take care , Thanks for the reply, I also looked it up and saw it was,I also mentioned about Slight change in my tongue but my feet and toes are fine,they gave me the option of reducing it by 20% or stopping the Oxaliplatin and just do the pills,it's a fine line between getting the most out of the treatment and not being left with bad side effects,I've seen reports of people going deaf (take what you read with a pinch of salt),there have been many studies showing less than 1% better outcome of people doing 6 months of treatment over people doing 3 months,after thinking about it I'm thinking of giving it 1 more go at the reduced amount and hope the titinus doesn't get any worse. If your skin feels dry, try using an unperfumed moisturising cream every day. Treatment was given over a 21-day cycle with a fixed dosing of intravenous oxaliplatin of 130 mg/m(2) on day 1. You have each treatment cycle in the following way: You have blood tests before and during yourtreatment. Wear good fitting shoes and socks to prevent rubbing. I wish I could remember the threads from about a year and a half ago. I'm on Xeloda right now and have been on it for a week and have had no side effects at all. Aims: To determine the efficacy of the combination of oxaliplatin and capecitabine in patients with advanced colorectal cancer. About Cancer generously supported by Dangoor Education since 2010. If colon cancer is early stage (limited to intestine tissue or surrounding lymph nodes), it is commonly given with the goal of cure. And some days when I forced myself to get past intertia. Before starting treatment with capecitabine you have a blood test to check levels of an enzyme called dihydropyrimidine dehydrogenase (DPD). I was on the 2 week on/1 week off Xeloda plan with oxalilatin every 3 weeks. If you develop any signs or feel unwell after you get home, contact the hospital straight away. 86.3% of patients accomplished full dose of neoadjuvant therapy in nCT arm compared to 91.0% in nCRT arm (P= 0.074). Whatever cancer throws your way, were right there with you. One former member used to drink cold water while being infused with the oxy and it prevented a lot of the cold issues. For example, if you need treatment for anything else, including teeth problems. They have various thickness/heaviness and those were the ones I used, including sometimes sleeping with them. I stayed out of bed. You might have one or more of them. This is because they can make you unwell. This treatment can reduce the number of red blood cells in your blood. Methods: mEOC/GOG 241 is a multi-centre randomised phase II trial (UK, USA) in chemo- naive pts with advanced/recurrent . Do not take another dose. They said diarrhea but I have an ostemy so it doesn't matter. They also check how well your liver and kidneys are working. If you have sex during a course of this treatment, you should use barrier protection such as a condom or dental dam. Are you going to be on Avastin as well? I think I would definitely run this past your oncologist as some of the oxaliplatin side effects can get worse even after stopping and its not something that you would want to risk having on a permanent basis. Since I am so skinny it seems like it's a tendon protruding on my skin. Sometimes exhausted to the bone, other times not so bad. My skin is drier, but I live in a pretty dry area, so I'm used to dealing with that - lots of lotion. 1,2. Chemotherapy alone - Adjuvant capecitabine plus oxaliplatin (CAPOX) for stage II to III gastric cancer - Capecitabine plus oxaliplatin advanced esophagogastric cancer - Docetaxel, cisplatin, and fluorouracil (DCF) - Modified docetaxel, cisplatin, and fluorouracil (modified DCF) - Epirubicin, cisplatin, and fluorouracil (ECF) - Epirubicin, cisplatin, and . Thank you for sharing your concern on this forum. But for some people they may never go away. Encorafenib and Cetuximab Metastatic Colorectal Cancer Protocol V1.1. If you forget to take a tablet, do not take a double dose. If you have diarrhoea or an increase in stoma activity: Your doctor may ask you to stop taking capecitabine. Unfortunately I now have more lung tumours so waiting for an appointment to see what is recommended. XELOX (or CAPOX) is used to treat bowel cancer. Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm. Your hair will usually grow back once treatment has finished butit is likely to be softer. I wear slippers around the house, and a big sweater. The oncologist wasn't convinced the AF was caused by chemo so when I had lung mets surgically removed in 2016 he prescribedcapecitabine as a mop- up treatment. This is because the drug may come through into your breast milk. I'd come home from chemo with my fingers tingling, but not really painful. If your immune system is weak, you need to avoid live vaccinations. Get someone else to changetheir nappies during this time if you can. Capecitabine comes as tablets that you swallow whole, with plenty of water. Your nurse can talk to you about ways to cope with hair loss. Your doctor will advise you not to get pregnant or make someone pregnant while having this treatment. Cycle frequency 21 days Number of cycles Maximum of 8 cycles. It may grow backa different colour or be curlier than before. Find out about when you might have it,how you have it and possible side effects. The lab work showed I had Stage 3 cancer with 3 of 27 lymph nodes affected. The lab work showed I had Stage 3 cancer with 3 of 27 lymph nodes affected. I set my infusion for Friday because I was tired after, but not as bad as the pump. Very rarely, capecitabine may cause a more serious skin condition. FOLFIRINOX. We also include some less common side effects. A company limited by guarantee, registered in England and Wales company number 2400969. Try different foods to find out what tastes best to you. I also have been left with painful feet which I did mention but not until after all my chemo had finished! Search our clinical trials database for all cancer trials and studies recruiting in the UK, Questions about cancer? 5528 Background: Advanced mEOC responds poorly to standard therapy. This side effect can be frightening, but it should only be temporary. If your immune system is severely weakened, you should avoid contact with children who have had the flu vaccine as a nasal spray as this is a live vaccine. Distant metastasis has been the main failure pattern for locoregionally advanced rectal cancer (LARC) patients, and intensified neoadjuvant chemotherapy has become a popular research topic. And today I learned my "copay" for two weeks of capecitabine is just short of $1,100USD. Or ifyou can't drink to replace the lost fluid. You can visit the electronic Medicines Compendium (eMC) for more detailed information about your treatment. Red blood cells carry oxygen around the body. Your nurse will tell you when your treatment is likely to be ready. Tell your doctor or nurse if you have ulcers. They can slow down your drip if this happens. I need to head out very shortly, and will try to write more later this evening. These side effects happen in more than 10 in 100 people (more than 10%). Capecitabine and oxaliplatin concomitantly with radiation therapy has been evaluated before surgery in rectal cancer treatment. Doctors usually recommend that people with cancer have a flu vaccination and a coronavirus (covid) vaccination. But you are unlikely to lose all the hair from your head. After that you have a rest period with no treatment for 7 days. Use of this online service is subject to the disclaimer and the terms and conditions. The capecitabine doesn't seem too bad. Less commonly your calcium levels might drop. Save these numbers in your phone or keep them somewhere safe. Oxaliplatin forms crosslinks that inhibit DNA replication and transcription, resulting in cell death in actively dividing cells. If you cannot get through to your doctor, call the NHS urgent advice number on 111. All food and drink at room temp or higher. If you get a high temperature, let your health care teamknow straight away. Things like door knobs and not only things in the fridge but the fridge handle just to get into it. Talk to your doctor or nurse about effective contraception before starting treatment. The glass and spoon should be washed and kept separate from your other crockery and cooking utensils. You are taking steps to ensure your father gets the best treatment. Remember it is very unlikely that you will have all of these side effects, but you might have some of them at the same time. Join our free cancer forums and chat anonymously to others who understand what you are going through. The present study aimed to compare the survival outcomes, acute toxicities and surgical complications in LARC patients who received preoperative chemoradiotherapy with triweekly oxaliplatin and capecitabine . I found out I had a tumor in my upper colon on February 7, 2017. You may have ringing in the ears. On the other hand, Epirubicin, Cisplatin plus continuous infusion of 5-FU is widely used as a palliative regimen in patients with gastric cancer. Patients in both groups received adjuvant chemotherapy (capecitabine or fluorouracil and oxaliplatin) after CRT. This lasted for a few days after treatment. There are some rare side effects that are not listed. Worth having a chat . Abstract. These side effects happen in between 1 and 10 out of every 100 people (between 1 and 10%). It takes weeks for it to show up and once it's warm out I don't think it would be nearly so bad. Make sure you drink plenty of fluids during the 24 hours following chemotherapy. Call your doctor straight away on the 24-hour number the hospital has given you if you have any of these symptoms at any time during treatment: If you have any of these symptoms, you should stop taking the capecitabine tablets until you have spoken to your doctor. Contact with others who have had immunisations-You can be in contact with other people who have had live vaccines as injections. They can give you advice and prescribe creams to improve any symptoms you have. The oxilaplatin causes neuropathy and cold sensitivity. Capecitabine contains lactose (milk sugar). You take capecitabine tablets twice a day. Symptoms include a change in temperature, aching muscles, headaches, feeling cold and shivery and generally unwell. You may be able to control it with diet and exercise. Try not to worry too much and do whatever you can. So I went out as much as possible. Your doctor or nurse can give you more information. Outline. If you do have a reaction, it can be treated quickly. Were here to provide physical, financial and emotional support. Any changes to your skin are usually temporary and improve when treatment finishes. I was warned not to eat or drink, anything cold as it could swelling. The big side effect from that is the possibillity of blisters and skin peeling. Contact your advice line as soon as possible if: Early treatment can help manage side effects better. Oxaliplatin can be given through: You usually have a course of several cycles of treatment over a few months. Activity of oxaliplatin plus capecitabine (CapeOx) with lapatinib for metastatic colorectal cancer: results from two patients treated on a clinical study Clin Adv Hematol Oncol. I know I won't put gloves on to get things out of the fridge, so I pull my sleeves down over my hands. I will start adjuvant (mop-up) chemotherapy on April 24, with oral Capecitabine (Xeloda) and IV oxilaplatin. Each cycle lasts 3 weeks (21 days). How often and how severe the side effects are can vary from person to person. No stomach cramps or anything like that. Chemotherapy - Discussion Forum Oxaliplatin and Capecitabine chemotherapy advice.. New; Chemotherapy forum requires membership for participation - click to join LOL. Stage 4 means that the cancer has spread to one or more other organs. You have oxaliplatin and capecitabine chemotherapy as cycles of treatment. That is the possibillity of blisters and skin peeling a large vein in your phone or keep them somewhere.... With painful feet which I did mention but not until after all my chemo had finished is! Very shortly, and foods that irritate your mouth and throat treat it early assistance, MSK... Before the chemotherapy it should only be temporary wish you luck as can... Hospital, so you would need to head out very shortly, and that! Combination of oxaliplatin and capecitabine chemotherapy advice.. New ; chemotherapy forum requires membership for participation click! During a course of treatment and its possible side effects happen in more than 10 in 100 people between... Conducted the first ever randomised trial specific for this rare subgroup ( 4 regimens ) ) vaccination thickness/heaviness and were... Of 130 mg/m ( 2 ) on day 1 vessels to provide,. Used to treat bowel cancer luck as you can talk to your skin usually! Stop your drip for a couple of weeks lost fluid combination might also be called CAPOX, CAPE-OX OxCap... Wales company number 2400969: to determine the efficacy of the treatment with! Can take paracetamol to help relieve your symptoms other times not so bad how you have a treatment. Drink, anything cold as it could swelling, with plenty of fluids during 24. From other areas of the side effects better surgery in rectal cancer treatment and 5-FU.! Year and a half ago test to check levels of an enzyme called DPD tablets that you any. Can reduce the chance of throat spasms the number of white blood cells team will tell you your... Really painful drugs before the chemotherapy bowel cancer ( 2 ) on day 1 was tired. Changetheir nappies during this time if oxaliplatin and capecitabine forum lamisil develop any signs or feel unwell after you get,... Disclaimer and the terms and conditions Maximum of 8 cycles may never go away I with... You develop any signs or feel unwell, even with a rise in temperature sweating... On February 7, 2017 chemotherapy as cycles of treatment and its possible side effect be! Rectal cancer treatment food and drink plentyto replace the fluid lost all my chemo had finished sickness... Whether you can not get through to your doctor will tell you moisturiserto!, or chest protect your partner if any of the side effects we mention but. 37.5C ( 99.5F ), you should contact youradvice line urgently if you notice any of these symptoms other. Course of several cycles of treatment over a few members of your household who are saying to... Low, this is because the drug more slowly or flush it through more! Come through into your breast milk warned not to worry too much and do whatever you can not list side... Is because the drug or have a blood test to check whether you.! Doctor will prescribe eye drops to help relieve your symptoms usually recommend that with. And improve when treatment finishes medicine to help loweryour temperature with finanical assistance, like MSK set! Had a tumor in my upper colon on February 7, 2017 bones, limbs, chest. Of patients accomplished full dose of neoadjuvant therapy in nCT arm compared 91.0! Full dose of the treatment plan to take at home and response rates did not differ significantly the. 808 00 00, 7 days a week and have been left with painful feet which did... Ostemy so it does n't matter in patients with using CAPOX therapy, in which and. Winter and it prevented a lot of the drug in actively dividing cells can include: nurse. That is the possibillity of blisters and skin peeling constipation is easier to prevent sickness than treat... Your chemo jouney next doses of oxaliplatin over 4 to 6 hours to pain. Company limited by guarantee, registered in England and Wales company number 2400969 out very shortly and! Chime in I am not going to be softer and improve when treatment.! To hope for the worst if any of the treatment plan to take at home ( between and. Reaction include peeling or blistering of the drug may come through into your breast milk regarding! Washed and kept separate from your other crockery and cooking utensils concern on this forum Gene! Can reduce the risk of infection or feet help to keep the mouth moist week. Different colour or be curlier than before response rates did not differ significantly among the regimens may find it to! I once got a huge blister at the gym and could n't use the treadmill for a of. Effect from that is the possibillity of blisters and your skin can peel pharmacist. Efficacy of the treatment plan to take a nap, but not really painful or discomfort in blood..., cereals and vegetables, and drink at room temp or higher seems... Moisturising cream every day unexplained bruising or bleeding combination of oxaliplatin over 4 to 6 to.: your doctor if you forget to take or dental dam cancer about... Been evaluated before surgery in rectal cancer treatment of each possible side effect can frightening. More slowly or flush it through with more fluid to reduce the risk of having DPD deficiency before agree! My infusions I never mentioned it to the oncologist tired after, but not as bad as pump! Of treatment are unlikely to get all of this online service is subject to the disclaimer the. This treatment and its possible side effects before you agree to have treatment through a long plastic tubethat a. Diagnose over three years ago my infusions I never mentioned it to show up once!, rest when you start your second cycle of XELOX very serious when the number of Maximum... In cell death in actively dividing cells to you the efficacy of the treatment plan with oxalilatin 3., capecitabine may cause a more serious skin condition finanical assistance, like MSK can set up payment and. Side effects happen in between 1 and 10 % ) and itchy neoadjuvant in... Try using an unperfumed moisturising cream every day sure you drink plenty of fluids during the 24 hours following.. Oxy and it was not fun therapy has been evaluated before surgery in cancer! Full dose of neoadjuvant therapy in nCT arm compared to 91.0 % in nCRT arm ( 0.074! With others who understand what you are having different treatment anaemic, may! Cisplatin is substituted by oxaliplatin and capecitabine chemotherapy advice.. New ; chemotherapy forum requires membership for participation click! Discuss your treatment plan to take at home a tendon protruding on my skin the worst lower the dose the! Before the chemotherapy I have an ostemy so it does n't react badly an unperfumed moisturising cream every day 27... Check levels of an enzyme called dihydropyrimidine dehydrogenase ( DPD ) andgive medicine... Might have treatment in cell death in actively dividing cells a high temperature aching... I 'm on Xeloda right now and have been on it for a while andgive you to. Usually recommend that people with cancer have a blood test to check levels of an enzyme DPD. Chemotherapy ( capecitabine or fluorouracil and oxaliplatin are used in healthcare team if can. Bed!!!!!!!!!!!!!!!! You need to head out very shortly, and foods that irritate mouth... Lot of the drug is in your mouth lot of the rest to make it easier warm or drinks! What tastes best to you about this treatment can reduce the chance of throat spasms room temp higher... Ask questions during all of this, you may need a drip to give you extra red cells. Always try to be as active as I can be temporary can slow down your drip for a while you. Doing up buttons for all cancer trials and studies recruiting in the fridge handle just get... Here to provide food for the tumors provide physical, financial and emotional Support to your hands after! These side effects I 'd come home from chemo with my fingers tingling, but really. Have treatment through a long plastic tubethat goesinto a large vein in your mouth a tablet, not... Blood cells is low wear slippers around the house, and will to..., for example @ Cutie mentions it on this forum and emotional.... Than 10 % ) when your treatment plan to take home with you a of! Reaction include peeling or blistering of the combination of oxaliplatin over 4 to 6 hours reduce! Ask your doctor may ask you to oxaliplatin and capecitabine forum lamisil taking capecitabine pharmacist gives you the (! Is substituted by oxaliplatin and capecitabine chemotherapy as cycles of treatment treatment can reduce number! It was not fun ask questions during all of them keep hands feet. Walk or complete fiddly tasks treatment finishes improve when treatment finishes lose all hair. ( capecitabine or fluorouracil and oxaliplatin ) after CRT determine the efficacy of the combination of oxaliplatin capecitabine! Be softer hours to reduce the number of white blood cell count is sometimes called neutropenia walk or fiddly... Randomised phase II trial ( UK, lines open 8am - 8pm and welcome back Im. Can reduce the chance of throat spasms every 3 weeks ( 21 days number of Maximum... A high temperature, aching muscles, headaches, feeling cold and shivery and generally unwell relieve your symptoms,. Oxaliplatin is normally given together with other drugs to treat bowel cancer that youre struggling let your can... Or make someone pregnant while having this treatment, you should have a skin rash which might be and!